Respiratory quotient (RQ) is increased during dark phase in Insr P1195L/ + mice under both ND and HFD P1195L/ + The decrease in fat accumulation in WAT and liver of Insr P1195L/ +/HFD mice suggested that these animals may have increased energy dissipation and/or fat usage
Huang PH, Xirasagar S, Chen JH, Cheng YF, Kuo NW, Lin HC
Reasonable markers to track: waist circumference, weight, resting heart rate, sleep quality, and a basic liver panel (ALT, AST) before and after long cycles
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It might balance neurotransmitters like dopamine and serotonin, showing promise in neurological conditions such as schizophrenia and encephalopathies
The lead author of the 2025 narrative review titled "Regeneration or Risk?" emphasized the urgent need for randomized controlled trials